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Rabbit Anti-IL-5/BF350 Conjugated antibody (bs-1318R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1318R-BF350
英文名稱 Rabbit Anti-IL-5/BF350 Conjugated antibody
中文名稱 BF350標記的白細胞介素5抗體
別    名 B Cell Differentiation Factor I; IL5; IL 5; Colony stimulating factor; Colony Stimulating Factor Eosinophil; EDF; Eosinophil; Eosinophil Differentiation Factor; IL 5; Interleukin 5; B-cell differentiation factor I; IL-5; IL5_RAT; Interleukin-5; T Cell Replacing Factor; T-cell replacing factor; Interleukin5; TRF.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 13kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse IL-5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Interleukin 5 is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide linked homodimeric glycoprotein with 115 amino acid residues in each chain. Known also as EDF (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two domain structure, with each domain showing significant homology to the cytokine fold in GMCSF, MCSF, IL2, IL4 and growth hormone. Human and mouse IL5 have 70% amino acid sequence homology.

Function:
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.

Subunit:
Homodimer; disulfide-linked.

Subcellular Location:
Secreted.

Similarity:
Belongs to the IL-5 family.

Database links:

Entrez Gene: 3567 Human

Omim: 147850 Human

SwissProt: P05113 Human

Unigene: 2247 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

白細胞介素-5(IL-5)的表達對嗜酸粒細胞(EOS)有浸潤聚集的作用,目前多用變態(tài)反應方面的研究。
支氣管哮喘的重要特征主要是慢性非特異性炎癥改變,其病因與發(fā)病機制十分復雜,白介素5在支氣管哮喘發(fā)病機理上,近年來受到了很大關注。
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