| 產(chǎn)品編號(hào) | IHC0674 |
| 英文名稱(chēng) | 14-3-3 alpha/beta/zeta/delta Ready-To-Use IHC Kit |
| 中文名稱(chēng) | 14-3-3 α/β/ζ/δ即用型免疫組化試劑盒 |
| 別 名 | 1110013I11Rik; 1300003C17Rik; 14-3-3; 14-3-3-zeta; 14-3-3beta; 14-3-3E; 14-3-3G; 14-3-3GAMMA; 14-3-3t; 14-3-3z; 14-3-3zeta; 1C5; 2700028P07Rik; AA409740; AI596267; AL022924; AU019196; AU020854; AU021156; D7Bwg1348e; Er; GW128; HEL-S-1; HEL-S-3; HEL-S-93; HEL2; HEL4; HME1; HS1; KCIP-1; MDCR; MDS; Mkrn3; Mme1; Msfs1; PPP1R170; R74690; SFN; XELAEV_18012695mg; XELAEV_18015318mg; XELAEV_18043238mg; XELAEV_18045999mg; YWHAA; YWHAB; ywhab-a; ywhab-b; YWHAD; YWHAE; YWHAG; ywhag-a; ywhag-b; YWHAQ; YWHAS; YWHAZ; 14 3 3 protein sigma; 14-3-3 protein sigma; 1433S_HUMAN; Epithelial cell marker protein 1; HME 1; MGC143283 |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
At least seven isoforms comprise the highly conserved 14-3-3 family of homo- and heterodimeric proteins that are abundantly expressed in all eukaryotic cells. Although more than seven isoforms of 14-3-3 have been described, some redundancies have appeared upon sequencing. The 14-3-3s are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. By interacting with Cdc25C, 14-3-3 regulates entry into the cell cycle and, through interaction with Bad, prevents apoptosis. Other proteins that have been shown to bind to 14-3-3s include members of the protein kinase C family, Cbl, IRS-1, polyoma middle-T antigen, nitrate reductase, S-raf and the IGF-1 receptor. Detection of 14-3-3 proteins in cerebrospinal fluid has been shown to be quite useful in the differential diagnosis of Creutzfeldt-Jakob disease and other prion diseases. SWISS: P31946 Gene ID: 7529 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Mouse testis tissue slide using IHC0674 (14-3-3 alpha/beta/zeta/delta Kit).
Immunohistochemical analysis of paraffin embedded Human testis tissue slide using IHC0674 (14-3-3 alpha/beta/zeta/delta Kit).
Immunohistochemical analysis of paraffin embedded Rat testis tissue slide using IHC0674 (14-3-3 alpha/beta/zeta/delta Kit).
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