| 產(chǎn)品編號(hào) | IHC0671H |
| 英文名稱 | Human Azurocidin/HBP Ready-To-Use IHC Kit |
| 中文名稱 | 人天青素/肝素結(jié)合蛋白即用型免疫組化試劑盒 |
| 別 名 | AZAMP; AZU; AZU1; CAP37; HBP; hHBP; HUMAZUR; NAZC; Azurocidin; Cationic Antimicrobial Protein CAP37; Heparin-Binding Protein |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Azurocidin, also called heparin-binding protein (HBP), is an inactive homolog of serine proteinases residing in granulocytes. Initially it was thought to have only activity against gram-negative bacteria. Later it was also found to act against gram-positive bacteria and C. albicans. Azurocidin is considered a family member of polymorphonuclear leukocytes- derived antimicrobial proteins like defensins, LL-37 and lysozyme. Azurocidin has been recognized as a player in the activation and modulation of the immune response and may act to alarm the immune system. The cationic domain at one side of the protein is essential for its antimicrobial activity. It is stored in azurophil granules as well as secretory granules and as a result partly released at early stage of extravasation. Azurocidin is involved in chemotaxis and activation of monocytes, cytokine release and phagocytosis leading to more efficient bacterial clearance. The primary targeted environment of azurocidin are cells in the bloodstream, that is the endothelial lining, and the extravascular surroundings. The interaction of azurocidin with leucocytes is mediated via beta 2-intergrins. High plasma levels of azurocidin might help with the identification of patients which are at risk in developing sepsis. SWISS: P20160 Gene ID: 566 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human spleen tissue slide using IHC0671H (Human Azurocidin/HBP Kit).
Immunohistochemical analysis of paraffin embedded Human purulent appendicitis tissue slide using IHC0671H (Human Azurocidin/HBP Kit).
Immunohistochemical analysis of paraffin embedded Human acute chorionitis tissue slide using IHC0671H (Human Azurocidin/HBP Kit).
Immunohistochemical analysis of paraffin embedded Human lung tissue slide using IHC0671H (Human Azurocidin/HBP Kit).
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