產(chǎn)品編號 | IHC0667H |
英文名稱 | Human CD50 Ready-To-Use IHC Kit |
中文名稱 | 人CD50即用型免疫組化試劑盒 |
別 名 | intercellular adhesion molecules-3; Intercellular adhesion molecule 3; ICAM-3; ICAM 3; CD50; CDW 50; CDW50; ICAM 3; ICAM R; ICAMR; CD 50; CD50 antigen; ICAM-R; ICAM3; ICAM3_HUMAN |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
CD50 (intracellular adhesion molecule 3, ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells, ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin, DC-SIGN), a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes. |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human spleen tissue slide using IHC0667H (Human CD50 Kit).
Immunohistochemical analysis of paraffin embedded Human colon tissue slide using IHC0667H (Human CD50 Kit).
|