| 產(chǎn)品編號(hào) | IHC0180 |
| 英文名稱 | BRD7 Ready-To-Use IHC Kit |
| 中文名稱 | 鼻咽癌相關(guān)轉(zhuǎn)錄調(diào)節(jié)蛋白即用型免疫組化試劑盒 |
| 別 名 | 75 kDa bromodomain protein; BP75; BRD 7; BRD7; BRD7_HUMAN; Bromodomain containing 7; bromodomain containing protein 7; Bromodomain-containing protein 7; CELTIX 1; CELTIX1; NAG4; Protein CELTIX-1 |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
IHC0180 is a ready-to-use IHC kit for staining of BRD7. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data. SWISS: Q9NPI1 Gene ID: 29117 BRD7可能參與了基因轉(zhuǎn)錄調(diào)控,是一個(gè)核轉(zhuǎn)錄調(diào)節(jié)蛋白。經(jīng)研究發(fā)現(xiàn)BRD7可能是通過Ras/MEK/ERK和Rb/E2F兩條通路影響細(xì)胞周期的進(jìn)程，使細(xì)胞停滯于G0/G1期，BRD7具有阻止細(xì)胞周期進(jìn)程的作用。BRD7蛋白尤其是在鼻咽癌的發(fā)病過程中發(fā)揮了十分重要作用，BRD7基因的過表達(dá)可通過調(diào)節(jié)MAPK及Wnt信號(hào)通路抑制鼻咽癌的生長(zhǎng)，并將鼻咽癌阻滯在G1/S期。 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human testicle tissue slide using IHC0180 (BRD7 IHC Kit).
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