| 產(chǎn)品編號 | bsm-60323R |
| 英文名稱 | SPINK1 Recombinant Rabbit mAb |
| 中文名稱 | 腫瘤相關(guān)胰蛋白酶抑制劑1重組兔單抗 |
| 別 名 | ISK1_HUMAN; Serine protease inhibitor Kazal-type 1; Pancreatic secretory trypsin inhibitor; PCTT; PSTI; TCP; TATI; Serine protease inhibitor Kazal type 1; Spink 3; Spink3; Tumor-associated trypsin inhibitor(TATI); |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | E5F9 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 6.2 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis. [provided by RefSeq, Oct 2008] Subcellular Location: Secreted. Database links: Entrez Gene: 6690 Human SwissProt: P00995 Human 絲氨酸蛋白酶抑制劑因子Kazal 1型(SPINK1)是蛋白酶抑制劑家族的成員之一。因其在卵巢癌，胰腺癌，肝細(xì)胞癌，結(jié)直腸癌，前列腺癌等惡性腫瘤的發(fā)生、發(fā)展及預(yù)后中發(fā)揮重要作用，因此，SPINK1作為一種腫瘤標(biāo)志物的臨床應(yīng)用受到廣泛關(guān)注。 |
| 產(chǎn)品圖片 |
Tissue: Human pancreas
Section type: Formalin fixed & Paraffin -embedded section
Retrieval method: High temperature and high pressure
Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:1000
Primary ab incubation condition: 1 hour at room temperature
Counter stain: Hematoxylin
Comment: Color brown is the positive signal for bsm-60323R
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