| 產(chǎn)品編號 |
bs-46541P |
| 英文名稱 |
Recombinant human NQO1 protein, His
|
| 中文名稱 |
重組人醌氧化還原酶蛋白 |
| 別 名 |
Azoreductase; Cytochrome b 5 reductase; DHQU; DIA 4; DIA4; Diaphorase (NADH/NADPH) (cytochrome b 5 reductase); Diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase (NADH/NADPH) (cytochrome b-5 reductase); Diaphorase (NADH/NADPH); Diaphorase 4; D |
| 理論分子量 |
33.18 kDa |
| 檢測分子量 |
34 |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
＞0.5 mg/ml |
| 物 種 |
Human |
| 序 列 |
1-274/274 |
| 純 度 |
>90% as determined by SDS-PAGE |
| 純化方法 |
AC |
| 內毒素 |
Not analyzed |
| 表達系統(tǒng) |
E.coli |
| 活性 |
Not tested |
| 標簽 |
His |
| 緩 沖 液 |
Supplied as solution form in PBS (pH7.5) or lyophilized from PBS (pH7.5). |
| 保存條件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
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