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IL-22 Rabbit pAb (bs-20683R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-20683R
英文名稱 IL-22 Rabbit pAb
中文名稱 白介素-22抗體
別    名 Interleukin-22; Il22; Iltif; ILTIFa; MGC129416; MGC129417; IL-10-related T-cell-derived-inducible factor; IL-TIF; ILTIF; IL-TIF alpha; Interleukin-22a; IL-22a; IL 21; IL D110; IL TIF; IL21; IL22; ILD110; interleukin 21; MGC79382; MGC79384; TIFa; TIFIL 23; TIFIL-23; TIFIL23; zcyto18; Cytokine Zcyto18.  
Specific References  (1)     |     bs-20683R has been referenced in 1 publications.
[IF=5.307] Xu Zhou. et al. Magnesium isoglycyrrhizinate ameliorates lipopolysaccharide-induced liver injury by upregulating autophagy and inhibiting inflammation via IL-22 expression. BIOORG CHEM. 2022 Nov;128:106034  IHC, WB ;  Mouse.  
研究領域 免疫學  生長因子和激素  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rat,Dog,Horse)
產(chǎn)品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 17 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human IL-22: 81-150/179 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq].

Function:
Cytokine that contributes to the inflammatory response in vivo.

Subcellular Location:
Secreted.

Similarity:
Belongs to the IL-10 family.

SWISS:
Q9GZX6

Gene ID:
50616

Database links:

Entrez Gene: 50616 Human

Entrez Gene: 50929 Mouse

Entrez Gene: 500836 Rat

Omim: 605330 Human

SwissProt: Q9GZX6 Human

SwissProt: Q9JJY9 Mouse

Unigene: 287369 Human

Unigene: 103585 Mouse

Unigene: 195879 Rat



IL-22是白介素-10家族的成員,主要是由激活的T 淋巴細胞產(chǎn)生的一類重要的細胞因子,除了在Th17細胞中高表達之外,在NK和NKT等細胞中也有表達,在組織損傷修復以及牛皮癬、肝炎、肺炎、腸炎等慢性炎癥中發(fā)揮重要作用.IL-22是繼IL-6和IL-10之后又一個參與炎癥反應和代謝調控的細胞因子,IL-22有可能成為干預脂肪肝發(fā)生發(fā)展的新方法。
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