| 產(chǎn)品編號(hào) | bs-12660R |
| 英文名稱 | SNRPB Rabbit pAb |
| 中文名稱 | 小核糖核蛋白SNRPB抗體 |
| 別 名 | B polypeptide of Sm protein; COD; RSMB_HUMAN; Sm B/B'; Sm B/Sm B'; Sm B/SmB'; Sm protein B/B''; Sm-B/B''; Small nuclear ribonucleoprotein polypeptide B; Small nuclear ribonucleoprotein polypeptide B/B'; Small nuclear ribonucleoprotein polypeptides B and B |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 24 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SNRPB: 1-100/240 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008] Function: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. Subcellular Location: Nucleus. Post-translational modifications: Methylated. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine. Similarity: Belongs to the snRNP SmB/SmN family. SWISS: P14678 Gene ID: 6628 Database links: Entrez Gene: 6628 Human Entrez Gene: 20638 Mouse Omim: 182282 Human SwissProt: P14678 Human SwissProt: P27048 Mouse Unigene: 83753 Human |
