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Placental alkaline phosphatase (PLAP) Rabbit pAb (bs-20015R)  
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產(chǎn)品編號(hào) bs-20015R
英文名稱 Placental alkaline phosphatase (PLAP) Rabbit pAb
中文名稱 堿性磷酸酶(胎盤型)抗體
別    名 Alkaline phosphatase; Alkaline phosphatase placental; Alkaline phosphatase placental type; Alkaline phosphatase Regan isozyme; ALP; Alp1; ALPP; FLJ61142; Germ-cell alkaline phosphatase; nagao isozyme; OTTHUMP00000164354; PALP; Placental alkaline phosphata  堿性磷酸酶胎盤型; 胎盤堿性磷酸酶;
研究領(lǐng)域 腫瘤  激酶和磷酸酶  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Mouse
產(chǎn)品應(yīng)用 WB=1:500-2000,Flow-Cyt=1μg/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Placental alkaline phosphatase 1: 41-140/535 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. [provided by RefSeq, Jul 2008]

Subunit:
Homodimer.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Tissue Specificity:
Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.

Similarity:
Belongs to the alkaline phosphatase family.

SWISS:
P05187

Gene ID:
250

Database links:

Entrez Gene: 250 Human

Omim: 171800 Human

SwissProt: P05187 Human

Unigene: 284255 Human



產(chǎn)品圖片
Sample: Hela(Human) Cell Lysate at 30 ug Primary: Anti-Placental alkaline phosphatase (bs-20015R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD
Blank control (blue line): Hep G2(fixed with 70% ethanol Overnight at 4℃). Primary Antibody (green line): Rabbit Anti-Placental alkaline phosphatase antibody (bs-20015R),Dilution: 1μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody (white blue line): Goat anti-rabbit IgG-PE, Dilution: 1μg /test.
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