| 產(chǎn)品編號 | bs-18646R |
| 英文名稱 | MAN2A2 Rabbit pAb |
| 中文名稱 | α-甘露糖苷酶2x抗體 |
| 別 名 | 3-1; 6-alpha-mannosidase; alpha-mannosidase 2x; alpha-mannosidase IIx; MA2A2_HUMAN; MAN IIx; MAN2A2; MANA2X; Mannosidase alpha class 2A member 2; Mannosyl-oligosaccharide 1; Mannosyl-oligosaccharide 1, 3-1, 6-alpha-mannosidase; MX. |
| 研究領(lǐng)域 | 細(xì)胞生物 新陳代謝 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 131 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MAN2A2: 1-100/1150 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
MAN2A2 is a single-pass type II membrane protein that localizes to the cisternae of the golgi and is involved in protein modification pathways. More specifically, MAN2A1 uses zinc as a cofactor to catalyze the first committed step in the formation of N-glycans, namely the hydrolysis of the terminal alpha-D-mannose residues in the oligosaccharide Man5(GlcNAc)3. Function: Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway. Subcellular Location: Golgi apparatus membrane. Similarity: Belongs to the glycosyl hydrolase 38 family. SWISS: P49641 Gene ID: 4122 Database links: Entrez Gene: 4122 Human Entrez Gene: 140481 Mouse Omim: 600988 Human SwissProt: P49641 Human SwissProt: Q8BRK9 Mouse Unigene: 116459 Human Unigene: 269245 Mouse |
| 產(chǎn)品圖片 |
Sample:
LOVO(Human) Cell Lysate at 30 ug
FHC(Human) Cell Lysate at 30 ug
Primary: Anti-MAN2A2 (bs-18646R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 131 kD
Observed band size: 131 kD
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