| 產(chǎn)品編號(hào) | bs-16822R |
| 英文名稱 | KRT28 Rabbit pAb |
| 中文名稱 | 細(xì)胞角蛋白28抗體 |
| 別 名 | CK-28; Cytokeratin-28; K1C28_HUMAN; K25D; K28; Keratin 25D; Keratin 28; Keratin; Keratin, type I cytoskeletal 28; Keratin-25D; Keratin-28; KRT25D; KRT28; type I cytoskeletal 28; Type I inner root sheath specific keratin 25 irs4; Type I inner root sheath-specific keratin-K25irs4. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 51 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KRT28: 161-260/464 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009] Function: Essential for the proper assembly of types I and II keratin protein complexes and the formation of keratin intermediate filaments in the inner root sheath (irs). Subunit: Heterotetramer of two type I and two type II keratins. Subcellular Location: Cytoplasm. Tissue Specificity: Strongly expressed in skin and scalp, and weak expression observed in thymus. In the hair follicle, expressed in Henle layer, Huxley layer and in the irs cuticle. Expression extends from the bulb region up to the point of differentiation into the three layers. Also present in the medulla of beard hair (at protein level). Similarity: Belongs to the intermediate filament family. SWISS: Q7Z3Y7 Gene ID: 162605 Database links: Entrez Gene: 162605 Human Entrez Gene: 70843 Mouse SwissProt: Q7Z3Y7 Human SwissProt: A6BLY7 Mouse Unigene: 59736 Human |
