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HCV NS5A transactivated protein 8 Rabbit pAb (bs-8158R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-8158R
英文名稱 HCV NS5A transactivated protein 8 Rabbit pAb
中文名稱 丙肝病毒NS5A反轉錄蛋白8抗體
別    名 BTB(POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; C15orf1; HCV NS5A transactivated protein 8; Hepatitis C virus NS5A transactivated protein 8; NS5ATP8; BTBD1_HUMAN.  
研究領域 細胞生物  免疫學  細胞周期蛋白  轉錄調節(jié)因子  細菌及病毒  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BTBD1/HCV NS5A transactivated protein 8: 401-482/482 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.

Function:
Probable substrate-specific adapter of an E3ubiquitin-protein ligase complex which mediates the ubiquitinationand subsequent proteasomal degradation of target proteins.

Subunit:
Interacts with topoisomerase 1 and with TRIM5 isoformDelta. Interacts with CUL3.

Subcellular Location:
Cytoplasm, P-body. Note=Cytoplasmic bodies.

Tissue Specificity:
Ubiquitous; higher levels in heart andskeletal muscle.

Similarity:
Contains 1 BTB (POZ) domain.

SWISS:
Q9H0C5

Gene ID:
53339

Database links:

Entrez Gene: 53339 Human

Entrez Gene: 83962 Mouse

Omim: 608530 Human

SwissProt: Q9H0C5 Human

SwissProt: P58544 Mouse

Unigene: 459149 Human

Unigene: 439893 Mouse



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