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UGCGL2 Rabbit pAb (bs-6714R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-6714R
英文名稱 UGCGL2 Rabbit pAb
中文名稱 二磷酸葡萄糖神經(jīng)酰胺葡萄糖基轉(zhuǎn)移酶2抗體
別    名 HUGT2; UGCGL 2; Moderately similar to UDP glucose:glycoprotein glucosyltransferase; UDP Glc glycoprotein glucosyltransferase 2; UDP glucose ceramide glucosyltransferase like 1; UDP glucose ceramide glucosyltransferase like 2; UDP glucose glycoprotein glucosyltransferase 2; UGT2; UGGG2_HUMAN.  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Rat (predicted: Mouse,Pig,Sheep,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 172 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UGCGL2: 201-300/1516 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 UDP-glucose:glycoprotein glucosyltransferase (UGT) is a soluble protein of the endoplasmic reticulum (ER) that selectively reglucosylates unfolded glycoproteins, thus providing quality control for protein transport out of the ER.[supplied by OMIM, Oct 2009]

Function:
Recognizes glycoproteins with minor folding defects. Reglucosylates single N-glycans near the misfolded part of the protein, thus providing quality control for protein folding in the endoplasmic reticulum. Reglucosylated proteins are recognized by calreticulin for recycling to the endoplasmic reticulum and refolding or degradation.

Subcellular Location:
Endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment.

Tissue Specificity:
Higher levels in kidney, pancreas, heart, and skeletal muscle.

Similarity:
Belongs to the glycosyltransferase 8 family.

SWISS:
Q9NYU1

Gene ID:
55757

Database links:

Entrez Gene: 55757 Human

Omim: 605898 Human

SwissProt: Q9NYU1 Human



產(chǎn)品圖片
Sample: Hela(Human) Cell Lysate at 30 ug H9C2(Rat) Cell Lysate at 30 ug Primary: Anti-UGCGL2 (bs-6714R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 172 kD Observed band size: 192 kD
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