產(chǎn)品編號 | bs-1054R |
英文名稱 | HDC Rabbit pAb |
中文名稱 | L-組氨酸脫羧酶抗體 |
別 名 | L-Histidine decarboxylase; EC 4.1.1.22; HDC; L-HDC; Histidine decarboxylase; DCHS_HUMAN. |
研究領(lǐng)域 | 免疫學(xué) 激酶和磷酸酶 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號 | |
交叉反應(yīng) | Human (predicted: Mouse,Rat,Pig,Cow,Chicken,Dog) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 74 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HDC: 351-450/662 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Histidine decarboxylase(HDC) is the enzyme that calalyses the conversion of histidine into histamine. It can be found in the histamine secreting ECL cells of some species, as well as in the mast cells.The biogenic amine histamine is an important modulator of numerous physiological processes, including neurotransmission, gastric acid secretion and smooth muscle tone. Function: Catalyzes the biosynthesis of histamine from histidine. Subunit: Homodimer. Similarity: Belongs to the group II decarboxylase family. SWISS: P19113 Gene ID: 3067 Database links: Entrez Gene: 3067 Human Entrez Gene: 15186 Mouse Omim: 142704 Human SwissProt: P19113 Human SwissProt: P23738 Mouse Unigene: 1481 Human Unigene: 18603 Mouse Unigene: 48653 Rat
主要用于多種變態(tài)反應(yīng)及炎性浸潤改變有關(guān)的研究。 |
產(chǎn)品圖片 |
Tissue/cell: human breast carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-HDC Polyclonal Antibody, Unconjugated(bs-1054R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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